1. A chemical reaction in which an acyl group is introduced into a molecule, typically replacing a hydrogen atom.
Usage: chemistry; technical

Examples

• Acylation is a common reaction used in organic synthesis to modify the structure of compounds.
• The acylation of amines produces amides, which are important in pharmaceutical chemistry.
• Friedel-Crafts acylation is a standard method for introducing acyl groups into aromatic rings.
• Protein acylation plays a crucial role in cell signaling and protein localization.
• The acylation reaction requires an acyl donor and a catalyst to proceed efficiently.