noun
- the loss of structural differentiation within a cell or group of cells often as a result of malignant transformation
Usage: medical; pathology
Examples
- The pathologist noted severe anaplasia in the tumor cells.
- Anaplasia is a hallmark of aggressive cancers.
- The degree of anaplasia helps determine the cancer’s grade.
- Microscopic examination revealed cellular anaplasia throughout the tissue sample.
- High-grade tumors typically show marked anaplasia.
- The oncologist explained that anaplasia indicates loss of normal cell structure.