noun
- a chemical reaction in which a carboxyl group (-COOH) is introduced into an organic molecule
Usage: chemistry, biochemistry
Examples
- Carboxylation of pyruvate is a key step in gluconeogenesis.
- The enzyme catalyzes the carboxylation of the substrate to form a new carboxylic acid.
- In photosynthesis, carboxylation of ribulose bisphosphate is the first step of the Calvin cycle.
- Carboxylation reactions are essential in many metabolic pathways.
- The carboxylation of amino acids produces compounds important for protein synthesis.