noun
- A broad-spectrum antibiotic drug used to treat bacterial infections, particularly those caused by gram-negative bacteria and rickettsiae.
Usage: medical/pharmaceutical; often abbreviated as CAP; use has declined due to risk of bone marrow suppression
Examples
- Chloramphenicol was once widely prescribed but is now reserved for serious infections.
- The doctor prescribed chloramphenicol to treat the patient's rickettsial infection.
- Chloramphenicol can cause aplastic anemia as a rare but serious side effect.
- Before fluoroquinolones became available, chloramphenicol was a common choice for gram-negative bacterial infections.
- The antibiotic chloramphenicol inhibits bacterial protein synthesis by binding to the ribosome.