1. A toxic condition caused by excessive use or overdose of cinchona alkaloids (such as quinine), characterized by symptoms including tinnitus, hearing loss, dizziness, and gastrointestinal disturbances.
Usage: medical; plural form of cinchonism; historically associated with antimalarial treatment

Examples

• Cinchonisms were commonly reported in patients who took excessive doses of quinine for malaria prevention.
• The symptoms of cinchonisms include ringing in the ears and temporary deafness.
• Early travelers to tropical regions sometimes suffered from cinchonisms due to overuse of cinchona bark remedies.
• Modern antimalarial protocols are designed to minimize the risk of cinchonisms.
• Doctors monitored patients for signs of cinchonisms when prescribing quinine-based treatments.