1. a state of complete emptiness or destruction
2. anguished misery or loneliness

Examples

• The hurricane left a scene of complete desolation in its wake.
• After the fire, only desolation remained where the forest once stood.
• The abandoned town was a picture of desolation.
• She felt overwhelming desolation after losing her best friend.
• The desolation in his eyes was heartbreaking to see.
• Years of war had brought nothing but desolation to the region.
• The empty house filled her with a sense of desolation.