1. to cause someone to lose their sense of direction or position
2. to cause someone to feel confused about a situation or what is happening

Examples

• The thick fog disoriented the hikers on the mountain trail.
• Moving to a new city can disorient even experienced travelers.
• The medication may disorient patients temporarily.
• The maze was designed to disorient visitors.
• Jet lag disoriented her for several days after the flight.
• The sudden change in leadership disoriented the entire team.