1. A physical or chemical change in the brain that is thought to be the basis of memory; a memory trace.
Usage: psychology, neuroscience; also spelled engram

Examples

• Neuroscientists study how engrammes form during learning and consolidation.
• The engramme is believed to involve changes in synaptic connections between neurons.
• Researchers are investigating whether engrammes can be artificially reactivated.
• The concept of the engramme dates back to early 20th-century psychology.
• Memory loss may result from damage to existing engrammes in the brain.