1. to inject venom into; to poison with venom
Usage: transitive verb; often used of snakes, spiders, and other venomous animals
2. to make bitter, spiteful, or malicious
Usage: transitive verb; figurative use

Examples

• The cobra's fangs envenomate its prey within seconds.
• A spider envenomated the insect with a single bite.
• His bitter words envenomated the conversation.
• The venom gland envenomated the wound as the snake struck.
• Years of resentment had envenomated their relationship.