1. The innermost layer of the pericardium (the membrane surrounding the heart), in direct contact with the heart muscle.
Usage: Medical/anatomical term; Also called visceral pericardium

Examples

• The epicardium is a thin serous membrane that adheres closely to the surface of the heart.
• During cardiac surgery, the surgeon must be careful not to damage the delicate epicardium.
• The epicardium secretes fluid that reduces friction as the heart beats.
• Inflammation of the epicardium can lead to pericarditis, causing chest pain.
• The epicardium is continuous with the parietal pericardium at the base of the great vessels.