1. a letter, especially a formal or instructive one
Usage: formal
2. any of the letters in the New Testament written by the apostles
Usage: religious

Examples

• The professor wrote a lengthy epistle to his former student.
• She received an epistle from her grandmother containing family news.
• The Epistle to the Romans is one of Paul’s most important letters.
• His epistle to the editor was published in the local newspaper.
• The ancient epistle was discovered among the archaeological artifacts.
• Paul’s epistles form a significant portion of the New Testament.