1. the farthest point or limit of something
2. a hand or foot
Usage: medical
3. the highest degree of something, especially something unpleasant

Examples

• The cabin was located at the northern extremity of the lake.
• Frostbite typically affects the extremities first.
• The doctor examined all four extremities for signs of injury.
• The extremity of the weather forced schools to close.
• She lived at the extremity of the village, far from the town center.
• The patient had poor circulation in his lower extremities.
• The extremity of his reaction surprised everyone.