1. The line of cells that produce gametes (sperm or eggs) and pass genetic material to offspring; the reproductive cells and their precursors in an organism.
Usage: biology, genetics; often used in contrast to somatic cells

Examples

• Mutations in the germline can be inherited by future generations.
• The germline is distinct from somatic cells, which do not pass traits to offspring.
• Germline editing raises ethical questions about modifying human heredity.
• Cancer can originate in germline cells or in somatic tissues.
• Scientists study germline development to understand how organisms reproduce.
• Germline mutations are responsible for many hereditary diseases.