noun
- An enzyme that catalyzes the introduction or removal of supercoils in DNA, essential for DNA replication and transcription in bacteria.
Usage: biochemistry; molecular biology; also called DNA gyrase
Examples
- Gyrase is a critical enzyme in bacterial cells that manages DNA topology.
- The antibiotic fluoroquinolone works by inhibiting bacterial gyrase.
- Researchers studied how gyrase unwinds supercoiled DNA during replication.
- Gyrase activity is essential for the survival of most bacteria.
- The enzyme gyrase relieves tension in the DNA double helix.