noun
- Plural of hydroxylation; chemical reactions in which a hydroxyl group (-OH) is introduced into an organic molecule.
Usage: chemistry; biochemistry; technical term
Examples
- Hydroxylations are critical steps in the metabolism of many drugs in the liver.
- The enzyme catalyzes multiple hydroxylations of the substrate molecule.
- Cytochrome P450 enzymes perform numerous hydroxylations in phase I drug metabolism.
- These hydroxylations increase the water solubility of lipophilic compounds.
- The study examined hydroxylations of aromatic compounds under various conditions.