noun
- An amino acid found abundantly in collagen and other proteins, formed by the hydroxylation of proline after protein synthesis.
Usage: biochemistry; technical term; commonly abbreviated as Hyp
Examples
- Hydroxyproline makes up about 10% of the amino acids in collagen.
- The stability of collagen depends partly on its high hydroxyproline content.
- Vitamin C is essential for the hydroxylation of proline to hydroxyproline in collagen synthesis.
- Hydroxyproline residues form hydrogen bonds that stabilize the collagen triple helix.
- Deficiency in vitamin C impairs hydroxyproline formation, leading to weakened connective tissue.