1. the inner layer of cells in an early embryo that gives rise to the endoderm
Usage: biology; embryology

Examples

• The hypoblast forms during the early stages of embryonic development.
• Scientists studied how the hypoblast contributes to organ formation.
• The hypoblast and epiblast are the two primary cell layers in the blastocyst.
• Researchers observed hypoblast migration in the developing embryo.
• The hypoblast eventually develops into the digestive system lining.
• Cell differentiation begins when the hypoblast separates from other layers.