1. in a way that cannot be corrected, cured, or repaired

Examples

• The ancient manuscript was irremediably damaged by the flood.
• Their relationship was irremediably broken after the betrayal.
• The patient’s condition had deteriorated irremediably.
• The company’s reputation was irremediably tarnished by the scandal.
• The ecosystem was irremediably altered by the oil spill.
• His vision was irremediably impaired by the accident.