1. to make someone annoyed or angry
2. to make a part of the body sore, red, or painful
Usage: medical

Examples

• The constant noise from construction irritates the neighbors.
• His habit of interrupting people really irritates me.
• The soap irritates my sensitive skin.
• Smoke from the fire irritates her eyes.
• The rough fabric irritates the wound.
• It irritates him when people are late to meetings.
• Pollen irritates my throat during allergy season.