noun
- An antibody produced by an individual that reacts against antigens present in other members of the same species.
Usage: medical/immunology; also called alloantibody
Examples
- Blood transfusion reactions can occur when isoantibodies in the recipient's plasma attack donor red blood cells.
- The presence of isoantibodies against ABO blood group antigens is common in human populations.
- Hemolytic disease of the newborn may develop when maternal isoantibodies cross the placenta.
- Isoantibodies are distinct from autoantibodies, which target the body's own antigens.
- Immunization with foreign tissue can stimulate the production of isoantibodies.