noun
- Chromosomes formed by duplication of one arm of a chromosome with loss of the other arm, resulting in two identical arms joined at a single centromere.
Usage: technical; genetics; plural form of isochromosome
Examples
- Isochromosomes are often observed in certain genetic disorders and cancers.
- The presence of isochromosomes can lead to monosomy of one arm and trisomy of the other.
- Researchers identified isochromosomes in the patient's karyotype analysis.
- Isochromosomes may arise from abnormal chromosome breakage and reunion during meiosis.