1. having no children or offspring
Usage: formal
2. having no outcome or result
Usage: formal; rare

Examples

• The elderly couple remained issueless throughout their long marriage.
• His issueless brother left his entire estate to charity.
• The king worried about dying issueless and leaving no heir to the throne.
• After years of trying, they accepted they would be issueless.
• The negotiations proved issueless, with no agreement reached.
• Her issueless efforts to reform the system left her frustrated.