noun
- a rare neurological condition characterized by an abnormally smooth brain surface due to the absence or underdevelopment of normal brain folds and ridges
Usage: medical term; also called smooth brain disease
Examples
- Lissencephaly is a congenital disorder that affects brain development before birth.
- Infants diagnosed with lissencephaly often experience severe developmental delays.
- The smooth appearance of the brain in lissencephaly can be seen on MRI scans.
- Children with lissencephaly may have difficulty with motor control and cognitive function.
- Lissencephaly results from a disruption in the normal migration of brain cells during fetal development.