1. crazy or insane; acting in a wild or irrational manner
Usage: informal; chiefly North American

1. past tense and past participle of 'loco': to make crazy or cause to act irrationally
Usage: informal; transitive

Examples

• He went completely locoed after losing his job.
• The heat and stress had locoed him by the end of the summer.
• She thought her brother was locoed for quitting such a good position.
• The wild horse seemed locoed, bucking and running in circles.
• That decision absolutely locoed the entire team.
• He's been acting locoed ever since the accident.