1. superlative form of lonely; most sad from being alone or without companions
Usage: superlative form
2. superlative form of lonely; most remote or isolated in location
Usage: superlative form

Examples

• She felt loneliest during the holidays when everyone else was with family.
• The lighthouse stood on the loneliest stretch of coastline.
• That was the loneliest night of his entire life.
• The loneliest road in America runs through Nevada’s desert.
• Even in a crowded room, he was often the loneliest person there.
• The loneliest cabin sat miles from the nearest neighbor.