noun
- a chromosomal condition in which one chromosome from a homologous pair is missing
Usage: medical; genetics
Examples
- Turner syndrome is caused by monosomy of the X chromosome.
- The genetic counselor explained that monosomy can lead to developmental disorders.
- Monosomy 21 is extremely rare and usually incompatible with life.
- The karyotype analysis revealed monosomy in chromosome 18.
- Most cases of monosomy result in miscarriage during early pregnancy.
- Scientists study monosomy to understand chromosomal abnormalities better.