1. superlative form of netty; most resembling or covered with nettles
Usage: chiefly British; informal
2. superlative form of netty; most irritating or annoying
Usage: informal; chiefly British

Examples

• The nettiest part of the garden was left untended for years.
• That was the nettiest comment he could have made in the situation.
• The path through the woods grew nettiest near the old fence.
• She had the nettiest disposition of anyone in the office.
• The nettiest weeds took over the abandoned lot.