noun
- Plural of nondisjunction; failures of chromosomes or chromatids to separate properly during cell division, resulting in unequal distribution of genetic material to daughter cells.
Usage: biology/genetics term; occurs during meiosis or mitosis
Examples
- Nondisjunctions during meiosis can produce gametes with an abnormal number of chromosomes.
- Down syndrome often results from nondisjunctions that occur during the formation of egg or sperm cells.
- The researcher studied nondisjunctions in fruit flies to understand chromosome segregation errors.
- Maternal age is a known risk factor for nondisjunctions leading to trisomy 21.
- Nondisjunctions can occur in both meiosis I and meiosis II, producing different outcomes.