1. not able to be reversed, undone, or changed back to a previous state

Examples

• The chemical reaction was nonreversible once it began.
• Climate change may cause nonreversible damage to the ecosystem.
• The surgery resulted in nonreversible changes to her vision.
• Once the contract is signed, the agreement becomes nonreversible.
• The aging process involves many nonreversible biological changes.
• The company’s decision to close the factory was nonreversible.