1. A class of synthetic stimulant drugs derived from phenmetrazine, used historically as appetite suppressants and in the treatment of obesity and narcolepsy.
Usage: pharmaceutical/medical; plural form; largely historical; many phenmetrazine derivatives have been withdrawn from markets due to safety concerns

Examples

• Phenmetrazines were commonly prescribed as diet pills in the mid-20th century.
• The class of phenmetrazines includes compounds that act as central nervous system stimulants.
• Regulatory agencies have restricted the use of many phenmetrazines due to cardiovascular risks.
• Phenmetrazines work by increasing the release of norepinephrine in the brain.
• Some phenmetrazines were combined with other drugs in weight-loss medications that were later recalled.