1. a chemical compound containing a three-ring structure with nitrogen and sulfur atoms, used as the basis for various drugs, especially antipsychotic and antihistamine medications
Usage: technical; chemistry and pharmacology
2. any drug derived from phenothiazine, commonly used to treat schizophrenia, psychosis, and severe nausea
Usage: medical

Examples

• Chlorpromazine is a phenothiazine that was one of the first antipsychotic medications developed.
• The doctor prescribed a phenothiazine to help manage the patient's severe psychiatric symptoms.
• Phenothiazines work by blocking dopamine receptors in the brain.
• Some phenothiazines are also used as antiemetics to prevent vomiting.
• The discovery of phenothiazine drugs revolutionized the treatment of mental illness in the mid-20th century.
• Researchers continue to study the long-term effects of phenothiazine use.