1. In a manner relating to or occurring at the presynapse (the part of a synapse that releases neurotransmitters); from the perspective of the transmitting neuron.
Usage: neuroscience/biology; technical

Examples

• The drug acts presynaptically to increase the release of dopamine.
• Presynaptically, the neuron packages neurotransmitters into vesicles.
• This receptor functions presynaptically to inhibit further transmitter release.
• The mutation affects presynaptically located proteins involved in synaptic transmission.
• Researchers found that the compound works presynaptically rather than on the receiving neuron.