1. a reversal or defeat in progress; an unexpected problem or difficulty
2. the distance that a building must be placed back from a property line or street
Usage: architecture; urban planning

Examples

• The injury was a major setback to his athletic career.
• Despite the financial setback, the company continued its expansion plans.
• The failed experiment represented only a temporary setback for the research team.
• Bad weather caused a setback in the construction schedule.
• The building code requires a 20-foot setback from the street.
• She overcame every setback with determination and hard work.