1. most easily offended or irritated; most sensitive to criticism or perceived slights
Usage: superlative form of touchy
2. most requiring careful handling; most delicate or sensitive to deal with
Usage: superlative form of touchy

Examples

• He’s the touchiest person in our office about constructive feedback.
• The budget discussion is always the touchiest topic at board meetings.
• She becomes the touchiest when she’s stressed about work.
• Immigration policy is often the touchiest subject in political debates.
• My grandmother is touchiest about comments regarding her cooking.
• The merger negotiations reached their touchiest point yesterday.