1. to turn something upside down or on its end
2. to cause great changes to something; to disrupt completely

Examples

• The strong wind upended the patio table.
• She upended the box to empty out all the contents.
• The new technology upended the entire industry.
• The scandal upended his political career.
• The earthquake upended their quiet lives.
• He upended the bucket to drain the water.
• The discovery upended everything scientists thought they knew.