1. to turn something upside down or on its end
2. to cause great changes to something; to disrupt completely

Examples

• The strong wind upends the trash cans on the street.
• She upends the box to empty out all the contents.
• The new technology upends traditional business models.
• The scandal upends his political career.
• The earthquake upends life in the small town.
• He upends the table in frustration.
• The discovery upends our understanding of history.